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Always seek professional advice relevant to your circumstances.16. Meston CM. A randomized, placebo-controlled, crossover study of ephedrine for SSRI-induced female sexual dysfunction.

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SNRIs and SSRIs, including Sertraline hydrochloride, have been associated with cases of clinically significant hyponatremia in elderly patients, who may be at greater sertraline cause drowsiness for this adverse reaction See Warnings and Precautions 5.Sertraline administration did not noticeably sertraline cause drowsiness either the plasma protein binding or the apparent volume of distribution of tolbutamide, suggesting that the decreased clearance was due to a change in the metabolism of the drug Sertraline 100 mg when administered to 10 healthy male subjects had no effect on the beta-adrenergic blocking ability of atenolol In a placebo-controlled trial in normal volunteers, administration of sertraline for 17 days including 200 mg/day for the last 10 days did not change serum digoxin levels or digoxin renal clearance Preclinical studies have shown sertraline to induce hepatic microsomal enzymes.

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